Benefits of Estrogen Therapy for Brain Fog During Perimenopause
For many women in their 40s and early 50s, the most unsettling symptom of the menopausal transition isn’t hot flashes or night sweats—it is the sudden, inexplicable loss of cognitive “sharpness.” Often described as brain fog, this experience can manifest as forgetting why you walked into a room, struggling to find common words mid-sentence, or a “fuzzy” feeling that makes complex decision-making feel like wading through sludge.
For years, these symptoms were dismissed as a byproduct of stress or “just getting older.” However, emerging neuroscience—led by researchers like Dr. Lisa Mosconi—has revealed that the female brain is highly sensitive to the fluctuation and eventual decline of estrogen. Estrogen therapy (ET) is increasingly being recognized not just as a treatment for physical discomfort, but as a critical tool for restoring cognitive clarity and protecting long-term brain health.
Defining the “Fog”: A Metabolic Shift, Not a Permanent Decline
Perimenopausal brain fog …
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